Description

Ethyl 3-Nitropropanoate is a versatile organic ester compound widely used as a key synthetic intermediate. Its value lies in the reactive nitro and ester functional groups, which enable its use in various organic synthesis pathways, including Michael additions and cyclization reactions. This chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to build complex molecular structures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing β-amino acids or nitroalkane derivatives.
• Agrochemical Synthesis: Used in the production of certain herbicides, fungicides, and plant growth regulators that require a nitropropanoate moiety.
• Fine Chemical Manufacturing: Serves as a precursor for dyes, pigments, and other specialty chemicals where the nitro group can be further transformed.
• Organic Synthesis Research: Employed in academic and industrial R&D for cyclization reactions, the preparation of heterocyclic compounds, and as a Michael acceptor.
• Flavor and Fragrance Industry: Potential intermediate in the synthesis of certain aroma chemicals, though specific applications depend on final product structure.

Basic Information

Product Name	Ethyl 3-Nitropropanoate
CAS No.	3590-37-2
Molecular Formula	C5H9NO4
Molecular Weight	147.13 g/mol
Synonyms	3-Nitropropionic Acid Ethyl Ester; Ethyl 3-Nitropropionate; Ethyl β-Nitropropionate; NSC 404058; Propanoic acid, 3-nitro-, ethyl ester; β-Nitropropionic Acid Ethyl Ester
EINECS	222-710-5

Quality Control

Our Ethyl 3-Nitropropanoate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing specifications such as assay (by GC or HPLC), identity confirmation (by IR or NMR), and impurity profiles. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure containers are kept tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.