Description

n-tert-Butyl-α-(4-Nitrophenyl)Nitrone is a specialized nitrone compound, widely recognized as a spin-trapping agent in electron paramagnetic resonance (EPR) spectroscopy. Its core value lies in its ability to effectively capture and stabilize transient free radicals, enabling their detection and study in complex chemical and biological systems. This makes it an essential research chemical for scientists and engineers in the fields of polymer chemistry, material science, pharmaceuticals, and biochemistry, where understanding radical-mediated processes is critical.

Application

• Spin Trapping Agent: Primary use in EPR/ESR spectroscopy for the detection and identification of short-lived free radicals in chemical reactions and biological samples.
• Polymerization Research: Used to study radical initiation, propagation, and termination mechanisms in polymer synthesis and degradation processes.
• Pharmaceutical R&D: Investigates the role of reactive oxygen species (ROS) and nitrogen species (RNS) in drug metabolism, toxicity, and disease pathways.
• Material Science: Applied in the analysis of radical processes in coatings, adhesives, and advanced material formulations to improve stability and performance.
• Antioxidant Studies: Serves as a tool to evaluate the radical-scavenging activity and efficacy of potential antioxidant compounds.
• Industrial Chemistry: Monitors radical intermediates in catalytic processes, oxidation reactions, and industrial chemical synthesis for optimization and safety.

Basic Information

Product Name	n-tert-Butyl-α-(4-Nitrophenyl)Nitrone
CAS No.	3585-88-4
Molecular Formula	C₁₁H₁₄N₂O₃
Molecular Weight	222.24 g/mol
Synonyms	PBN-NO₂; 4-Nitro-PBN; N-tert-Butyl-α-(4-nitrophenyl)nitrone; α-(4-Nitrophenyl)-N-tert-butylnitrone; 2-Methyl-2-(4-nitrobenzylideneamino)propan-1-ol-1-oxyl (tautomer); 4-Nitro-Phenyl N-tert-Butyl Nitrone; Nitrone Spin Trap PBN-NO₂; N-t-Butyl-α-(4-nitrophenyl)nitrone
EINECS	Contact for details

Quality Control

Our n-tert-Butyl-α-(4-Nitrophenyl)Nitrone is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive spectroscopic applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and EPR to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity, the product should be stored under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
EPR Performance Test	Effective spin-trapping capability confirmed

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.