Description

1-Phenyl-2,3,4,9-tetrahydro-1H-β-carboline hydrochloride is a complex heterocyclic organic compound belonging to the β-carboline alkaloid class. This compound serves as a crucial advanced pharmaceutical intermediate and a versatile scaffold in medicinal chemistry research. It is primarily sought by pharmaceutical R&D and fine chemical synthesis sectors for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Core scaffold for structure-activity relationship (SAR) studies and the development of new β-carboline derivatives with potential biological activity.
• Biochemical Tool Compound: Used in pharmacological studies to investigate interactions with enzymes and receptors, such as monoamine oxidases (MAOs).
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Organic Synthesis: Versatile precursor for synthesizing more complex polycyclic aromatic and heteroaromatic systems in academic and industrial settings.

Basic Information

Product Name	1-Phenyl-2,3,4,9-tetrahydro-1H-β-carboline hydrochloride
CAS No.	3574-01-4
Molecular Formula	C₁₇H₁₇ClN₂
Molecular Weight	284.78 g/mol
Synonyms	1-Phenyl-1,2,3,4-tetrahydro-β-carboline hydrochloride; 1-Phenyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole hydrochloride; Norharmane-1-phenyl hydrochloride; 9H-Pyrido[3,4-b]indole, 1,2,3,4-tetrahydro-1-phenyl-, hydrochloride; Phenyltetrahydro-β-carboline HCl; 1-Phenyl-THBC hydrochloride
EINECS	Contact for details

Quality Control

Our 1-Phenyl-2,3,4,9-tetrahydro-1H-β-carboline hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets exacting standards for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.