Description

(3As,7R)-3',3Aβ,4,4',5,6,8,8Aβ-Octahydro-8β-Hydroxy-6α,8-Dimethyl-3-Methylenespiro[7H-Cyclohepta[B]Furan-7,2'(5'H)-Furan]-2,5'(3H)-Dione is a complex spirocyclic diterpenoid derivative with a unique fused furan structure. This compound is of significant interest in advanced organic synthesis and pharmaceutical research due to its intricate molecular architecture, which serves as a valuable chemical intermediate for developing novel bioactive molecules. It is primarily utilized by research institutions and development laboratories in the pharmaceutical and agrochemical sectors for exploring new synthetic pathways and potential therapeutic or pesticidal agents.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the research and development of new drug candidates, particularly for complex natural product analogs.
• Agrochemical Research: Used in the synthesis of novel compounds with potential herbicidal, insecticidal, or fungicidal activity.
• Organic Synthesis Reference Standard: Acts as a high-purity standard for analytical method development and validation in quality control laboratories.
• Academic & Industrial R&D: Employed in methodological studies for constructing complex spirocyclic and polycyclic frameworks.
• Chemical Biology Probe: Utilized to investigate biological pathways and protein interactions due to its distinctive three-dimensional structure.

Basic Information

Product Name	(3As,7R)-3',3Aβ,4,4',5,6,8,8Aβ-Octahydro-8β-Hydroxy-6α,8-Dimethyl-3-Methylenespiro[7H-Cyclohepta[B]Furan-7,2'(5'H)-Furan]-2,5'(3H)-Dione
CAS No.	3533-47-9
Molecular Formula	C17H20O5
Molecular Weight	304.34 g/mol
Synonyms	8β-Hydroxy-6α,8-dimethyl-3-methylenespiro[7H-cyclohepta[b]furan-7,2'(5'H)-furan]-2,5'(3H)-dione; Spiro[7H-cyclohepta[b]furan-7,2'(5'H)-furan]-2,5'(3H)-dione, 3',3aβ,4,4',5,6,8,8aβ-octahydro-8β-hydroxy-6α,8-dimethyl-3-methylene-, (3aS,7R)-; CAS 3533-47-9; Diterpenoid Spirofuran Dione; Furanospirodione Derivative
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Each batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and MS to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical parameters such as assay, chiral purity, and impurity profile. We support cGMP and ISO-aligned practices for research-grade materials to ensure batch-to-batch consistency and reliability for your development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.