Description

4-Bromo-2-Chloroacetanilide is a halogenated acetanilide derivative, a key organic intermediate prized for its versatile reactivity. This compound is essential for the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily required by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with halogenated aromatic structures.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and insecticides, where its halogen atoms provide key sites for further functionalization.
• Organic Synthesis Reagent: Serves as a versatile precursor in cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination, for creating complex biaryl and aniline derivatives.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of specialized azo dyes and high-performance pigments.
• Material Science Research: Employed in the development of organic electronic materials, ligands for catalysts, and monomers for specialty polymers.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-Bromo-2-Chloroacetanilide
CAS No.	3460-23-9
Molecular Formula	C8H7BrClNO
Molecular Weight	248.51 g/mol
Synonyms	N-(4-Bromo-2-chlorophenyl)acetamide; 2-Chloro-4-bromoacetanilide; Acetamide, N-(4-bromo-2-chlorophenyl)-; 4-Bromo-2-chloro-N-phenacylacetamide; 4-Bromo-2'-chloroacetanilide; 2-Chloro-4'-bromoacetanilide; NSC 403697
EINECS	222-408-9

Quality Control

Our 4-Bromo-2-Chloroacetanilide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our production adheres to cGMP guidelines where applicable, ensuring reliability for critical pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of heat. The container should be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.