Description

1-O,2-O,3-O,4-O,6-o-Pentamethyl-β-D-Mannopyranose is a fully methylated derivative of mannose, serving as a crucial protected sugar intermediate in synthetic organic chemistry. This compound matters because it provides a stable, non-reactive scaffold for the controlled synthesis of complex carbohydrates, glycoconjugates, and chiral building blocks. It is primarily needed by research institutions and industrial laboratories focused on pharmaceutical development, carbohydrate chemistry, and the production of specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel glycosidase inhibitors, antiviral agents, and other carbohydrate-based therapeutics.
• Glycochemistry Research: Used as a protected mannose donor in the stepwise construction of oligosaccharides and complex glycans for biological studies.
• Chiral Pool Synthesis: Serves as a source of chirality for the asymmetric synthesis of natural products and other optically active molecules.
• Chemical Biology Probes: Employed in the development of labeled sugars and metabolic probes to study glycosylation pathways.
• Standards and Reference Materials: Utilized as an analytical standard in chromatography (HPLC, GC) for method development and quality control in carbohydrate analysis.

Basic Information

Product Name	1-O,2-O,3-O,4-O,6-o-Pentamethyl-β-D-Mannopyranose
CAS No.	3445-71-4
Molecular Formula	C₁₁H₂₀O₆
Molecular Weight	248.27 g/mol
Synonyms	Pentamethyl-β-D-mannopyranose; 1,2,3,4,6-Penta-O-methyl-D-mannopyranose; β-D-Mannopyranose, pentamethyl ether; Methyl 2,3,4,6-tetra-O-methyl-β-D-mannopyranoside; Per-O-methyl-D-mannose; 3445-71-4; Pentamethyl mannose
EINECS	222-357-6

Quality Control

Our 1-O,2-O,3-O,4-O,6-o-Pentamethyl-β-D-Mannopyranose is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation [α]²⁰D	-60° to -65° (c=1 in CHCl₃)
Melting Point	78°C - 82°C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.