Description

Endo-8-Isopropyl-8-Azabicyclo[3.2.1]Octan-3-Ol is a high-purity, bicyclic organic compound featuring a tropane alkaloid core structure. This specialized intermediate is critical for the synthesis of complex pharmaceutical molecules, offering a valuable chiral scaffold for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anticholinergic drug research.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new therapeutic candidates.
• Asymmetric Synthesis: Used in the preparation of enantiomerically pure compounds due to its rigid, defined stereochemistry.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Fine Chemical Synthesis: An intermediate in multi-step synthetic routes for producing high-value, complex organic molecules.

Basic Information

Product Name	Endo-8-Isopropyl-8-Azabicyclo[3.2.1]Octan-3-Ol
CAS No.	3423-25-4
Molecular Formula	C10H19NO
Molecular Weight	169.26 g/mol
Synonyms	8-Isopropyl-8-azabicyclo[3.2.1]octan-3-ol (endo-); 3-endo-Hydroxy-8-isopropyl-8-azabicyclo[3.2.1]octane; 8-Isopropylnortropan-3-ol; Nortropine isopropyl ether; 3-endo-Hydroxy-8-isopropylnortropane; 8-Azabicyclo[3.2.1]octan-3-ol, 8-(1-methylethyl)-, (3-endo)-; Tropine isopropyl ether derivative
EINECS	Contact for details

Quality Control

Our Endo-8-Isopropyl-8-Azabicyclo[3.2.1]Octan-3-Ol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.