Description

n-Me-Ile-Ome Hcl is a protected amino acid derivative, specifically the methyl ester hydrochloride salt of N-methylisoleucine. This compound is a crucial chiral building block in advanced organic synthesis, offering precise control over stereochemistry and molecular structure. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel peptides, peptidomimetics, and active pharmaceutical ingredients (APIs).

Application

• Peptide Synthesis: Serves as a key intermediate in solid-phase and solution-phase peptide synthesis for introducing the N-methylisoleucine moiety.
• Pharmaceutical Research: Used in the R&D of therapeutic peptides and peptidomimetics targeting various diseases.
• Medicinal Chemistry: Acts as a building block for creating compound libraries and optimizing lead molecules in drug discovery programs.
• Bioconjugation: Employed in the synthesis of peptide-based conjugates for diagnostic and targeted drug delivery applications.
• Chemical Biology: Utilized as a tool compound to study protein-protein interactions and enzyme mechanisms.
• Academic Research: Fundamental research in synthetic organic chemistry and amino acid chemistry.

Basic Information

Product Name	n-Me-Ile-Ome Hcl
CAS No.	3339-43-3
Molecular Formula	C8H18ClNO2
Molecular Weight	195.69 g/mol
Synonyms	N-Methyl-L-isoleucine methyl ester hydrochloride; Methyl (2S,3S)-2-(methylamino)-3-methylpentanoate hydrochloride; L-N-Methylisoleucine methyl ester HCl; (2S,3S)-2-(Methylamino)-3-methylpentanoic acid methyl ester hydrochloride; N-Me-Ile-OMe·HCl; N-Methylisoleucine methyl ester hydrochloride salt
EINECS	Contact for details

Quality Control

Our n-Me-Ile-Ome Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment and opened under dry, inert conditions when possible to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.