Description

2-Chloro-4-Hydroxybenzonitrile is a versatile halogenated aromatic nitrile compound that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both a phenolic hydroxyl and a chloro substituent, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is essential for research and production in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with antibacterial or antifungal properties.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and plant growth regulators, leveraging its halogen and nitrile functionalities.
• Liquid Crystal Materials: Serves as a building block for the production of advanced liquid crystal compounds used in display technologies.
• Polymer Chemistry: Acts as a monomer or modifier in the synthesis of high-performance polymers and resins.
• Dyestuff and Pigment Intermediate: Utilized in the production of specialized dyes and organic pigments.
• Chemical Research & Development: Employed as a standard reagent in organic synthesis laboratories for method development and scale-up studies.

Basic Information

Product Name	2-Chloro-4-Hydroxybenzonitrile
CAS No.	3336-16-1
Molecular Formula	C7H4ClNO
Molecular Weight	153.56 g/mol
Synonyms	4-Hydroxy-2-chlorobenzonitrile; 2-Chloro-4-cyanophenol; 2-Chloro-4-hydroxybenzenecarbonitrile; 4-Cyano-3-chlorophenol; 3-Chloro-4-hydroxybenzonitrile; 2-Chloro-4-hydroxyphenyl cyanide; 2-Chloro-4-cyanophenol; Benzonitrile, 2-chloro-4-hydroxy-
EINECS	222-065-7

Quality Control

Our 2-Chloro-4-Hydroxybenzonitrile is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable, and all materials are supported by comprehensive analytical documentation. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee compliance with your specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	145 - 149 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.