Description

2-Azabicyclo[2.2.2]octan-3-one is a versatile and structurally significant bicyclic lactam, serving as a key synthetic intermediate in advanced organic chemistry. Its rigid, bridged framework makes it a valuable building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting the central nervous system.
• Chiral Auxiliary & Catalyst Synthesis: Used to construct chiral ligands and organocatalysts for asymmetric synthesis, enabling the production of enantiomerically pure compounds.
• Agrochemical Research: Serves as a scaffold for developing novel herbicides, fungicides, and insecticides with unique modes of action.
• Material Science Monomer: Employed in the research of specialty polymers and advanced materials with specific thermal or mechanical properties.
• Academic & Discovery Chemistry: A valuable tool in academic laboratories and contract research organizations (CROs) for methodology development and exploring new chemical space.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex natural product analogs and other high-value specialty chemicals.

Basic Information

Product Name	2-Azabicyclo[2.2.2]octan-3-one
CAS No.	3306-69-2
Molecular Formula	C7H11NO
Molecular Weight	125.17 g/mol
Synonyms	2-Azabicyclo[2.2.2]octan-3-one; 3-Quinuclidinone; 1-Azabicyclo[2.2.2]octan-2-one; NSC 403697; Quinuclidin-3-one; Tropinone analog; Bicyclic lactam
EINECS	221-987-7

Quality Control

Our 2-Azabicyclo[2.2.2]octan-3-one is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chromatography and spectroscopy, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with agreed specifications. Our quality commitment supports your regulatory needs for research and cGMP-grade production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider maintaining the product under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.