Description

6-Bromo-3,4-Dihydro-1H-Quinolin-2-One is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. Its core quinolinone scaffold, functionalized with a bromine atom, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for use in medicinal chemistry programs, lead optimization, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Acts as a building block for organic electronic materials, such as charge-transport layers or light-emitting components, due to its conjugated system.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry and the development of chemical tools for studying biological processes.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development, heterocyclic chemistry studies, and exploring new reaction pathways.
• Custom Synthesis: A starting material for the tailored synthesis of more complex, bromine-substituted quinoline and quinolinone derivatives for specialized client projects.

Basic Information

Product Name	6-Bromo-3,4-Dihydro-1H-Quinolin-2-One
CAS No.	3279-90-1
Molecular Formula	C9H8BrNO
Molecular Weight	226.07 g/mol
Synonyms	6-Bromo-1,2,3,4-tetrahydro-2-quinolinone; 6-Bromo-2-oxo-1,2,3,4-tetrahydroquinoline; 6-Bromotetrahydro-2-quinolone; 2-Quinolinone, 6-bromo-3,4-dihydro-; 6-Bromo-3,4-dihydro-2(1H)-quinolinone; 6-Bromo-1,2,3,4-tetrahydroquinolin-2-one; 6-Bromocarbostyril
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.