Description

3-Oxa-1-Azaspiro[4.5]Decane-2,4-Dione is a specialized heterocyclic compound featuring a unique spirocyclic structure, serving as a versatile building block in advanced organic synthesis. This high-purity intermediate is critical for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals, where its defined stereochemistry and functional groups enable precise molecular construction. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for creating complex molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its spirocyclic scaffold for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for producing polymers with specific thermal or mechanical properties.
• Academic & Industrial R&D: A valuable compound for methodological studies in organic chemistry and process development.

Basic Information

Product Name	3-Oxa-1-Azaspiro[4.5]Decane-2,4-Dione
CAS No.	3253-43-8
Molecular Formula	C8H11NO3
Molecular Weight	169.18 g/mol
Synonyms	1-Azaspiro[4.5]decane-2,4-dione, 3-oxa-; 3-Oxa-1-azaspiro[4.5]decane-2,4-dione; 2,4-Dioxo-3-oxa-1-azaspiro[4.5]decane; 1-Aza-3-oxaspiro[4.5]decane-2,4-dione; NSC 163044; Spiro[cyclohexane-1,2'-[1,3]oxazolidine]-3',5'-dione
EINECS	221-857-7

Quality Control

Our 3-Oxa-1-Azaspiro[4.5]Decane-2,4-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.