Description

1-(3-Chloro-2-Hydroxyphenyl)Ethan-1-One is a versatile chlorinated aromatic ketone that serves as a critical synthetic intermediate. Its unique structure, featuring both a phenolic hydroxyl and an acetyl group ortho to a chlorine atom, makes it a valuable building block for constructing more complex molecules. This compound is primarily sought by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for synthesizing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with benzofuran or related heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides, leveraging its halogenated phenolic structure.
• Organic Synthesis Building Block: Employed in research laboratories for constructing complex organic molecules, including ligands for catalysis and materials science precursors.
• Dye and Pigment Intermediate: Serves as a starting material for the production of certain specialized dyes and organic pigments.
• Chemical Research & Development: Utilized in method development and as a standard or reagent in various chemical research applications.

Basic Information

Product Name	1-(3-Chloro-2-Hydroxyphenyl)Ethan-1-One
CAS No.	3226-34-4
Molecular Formula	C8H7ClO2
Molecular Weight	170.59 g/mol
Synonyms	3'-Chloro-2'-hydroxyacetophenone; 1-(3-Chloro-2-hydroxyphenyl)ethanone; 2-Acetyl-6-chlorophenol; 3-Chloro-2-hydroxyacetophenone; 2-Hydroxy-3-chloroacetophenone; o-Hydroxy-m-chloroacetophenone; NSC 403697; 3-Chlorosalicyloyl methyl
EINECS	221-751-0

Quality Control

Our 1-(3-Chloro-2-Hydroxyphenyl)Ethan-1-One is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from techniques such as HPLC, GC, NMR, and IR spectroscopy. Our quality commitment ensures the material is suitable for demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Recommended storage temperature is between 15°C and 25°C. Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	92°C - 96°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.