Description

5-(Chloromethyl)Isoxazole-3-Carboxylic is a versatile heterocyclic building block with a reactive chloromethyl group and a carboxylic acid functionality. This compound is of significant value in organic synthesis, particularly in the pharmaceutical and agrochemical sectors, due to its bifunctional reactivity which allows for selective derivatization. It is primarily sought after by research chemists and process development scientists for constructing complex molecules, including active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the isoxazole scaffold.
• Chemical Research & Development: A valuable reagent for constructing diverse heterocyclic libraries and exploring new chemical spaces in academic and industrial R&D.
• Ligand and Material Precursor: Serves as a starting material for synthesizing specialized ligands for catalysis or functional materials.
• Custom Synthesis Projects: Employed in contract manufacturing and custom synthesis for producing specific, high-value intermediates on a commercial scale.

Basic Information

Item	Detail
Product Name	5-(Chloromethyl)Isoxazole-3-Carboxylic Acid
CAS No.	3209-41-4
Molecular Formula	C5H4ClNO3
Molecular Weight	161.54 g/mol
Synonyms	5-(Chloromethyl)-1,2-oxazole-3-carboxylic acid; 5-(Chloromethyl)isoxazole-3-carboxylic acid; 3-Isoxazolecarboxylic acid, 5-(chloromethyl)-; 5-Chloromethyl-3-carboxyisoxazole; 5-Chloromethylisoxazole-3-carboxylic acid; 3209-41-4; 5-(Chloromethyl)-3-isoxazolecarboxylic acid
EINECS	Contact for details

Quality Control

Our 5-(Chloromethyl)Isoxazole-3-Carboxylic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.