Description

1-[(3,4-Dihydroxyphenyl)Methyl]-1,2,3,4-Tetrahydroisoquinoline-6,7-Diol Hydrochloride is a high-purity synthetic intermediate and research chemical of significant interest in pharmaceutical development. Its complex molecular structure, featuring multiple phenolic hydroxyl groups, makes it a valuable precursor for the synthesis of bioactive compounds. This product is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical suppliers focused on creating novel therapeutic agents, particularly in the fields of neurology and cardiology.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex alkaloids and potential drug candidates targeting neurological pathways.
• Biochemical Research: Used as a reference standard or substrate in enzymatic studies and receptor binding assays due to its catechol structure.
• Precursor for Neuroactive Compounds: Serves as a critical starting material for the development of tetrahydroisoquinoline derivatives with potential pharmacological activity.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for constructing complex molecules with specific chiral centers and functional groups.
• Academic & Institutional Research: Utilized in universities and research institutes for studying structure-activity relationships (SAR) and metabolic pathways.

Basic Information

Product Name	1-[(3,4-Dihydroxyphenyl)Methyl]-1,2,3,4-Tetrahydroisoquinoline-6,7-Diol Hydrochloride
CAS No.	3184-36-9
Molecular Formula	C₁₆H₁₇NO₄·HCl
Molecular Weight	323.77 g/mol
Synonyms	Norlaudanosoline Hydrochloride; 6,7-Dihydroxy-1-(3,4-dihydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline Hydrochloride; 1-(3,4-Dihydroxybenzyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline Hydrochloride; THIQ-6,7-diol Hydrochloride; Tetrahydropapaveroline Hydrochloride; NSC 169777; Laudanosoline Hydrochloride (common misnomer)
EINECS	221-694-8

Quality Control

Our 1-[(3,4-Dihydroxyphenyl)Methyl]-1,2,3,4-Tetrahydroisoquinoline-6,7-Diol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.