Description

2-(Chloromethyl)-3-(2-Methylphenyl)-4(3H)-Quinazolinone is a specialized heterocyclic organic compound that serves as a crucial synthetic intermediate in advanced pharmaceutical and agrochemical research. Its unique quinazolinone core, functionalized with chloromethyl and o-tolyl groups, makes it a versatile building block for constructing molecules with targeted biological activity. This high-purity intermediate is primarily sought by R&D chemists and process development scientists in the pharmaceutical, crop protection, and fine chemical industries for the synthesis of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly those targeting kinase inhibition, anti-inflammatory, or anticancer pathways.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactive quinazolinone scaffold.
• Chemical Biology & Proteomics: Serves as a precursor for activity-based probes or affinity tags to study enzyme function and protein interactions.
• Material Science: Potential monomer or precursor for creating specialty polymers and advanced organic materials with specific electronic or photophysical properties.
• Academic & Contract Research: Essential reagent for methodological development and exploratory synthesis in university and CRO laboratory settings.

Basic Information

Product Name	2-(Chloromethyl)-3-(2-Methylphenyl)-4(3H)-Quinazolinone
CAS No.	3166-54-9
Molecular Formula	C₁₆H₁₃ClN₂O
Molecular Weight	284.74 g/mol
Synonyms	3-(2-Methylphenyl)-2-(chloromethyl)-4(3H)-quinazolinone; 2-(Chloromethyl)-3-o-tolyl-4(3H)-quinazolinone; 4(3H)-Quinazolinone, 2-(chloromethyl)-3-(2-methylphenyl)-; NSC 163044; 3-(2-Methylphenyl)-2-(chloromethyl)quinazolin-4(3H)-one; 2-Chloromethyl-3-(o-tolyl)-4(3H)-quinazolinone
EINECS	221-637-9

Quality Control

Every batch of 2-(Chloromethyl)-3-(2-Methylphenyl)-4(3H)-Quinazolinone is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.