Description

1-Phenylmethoxycarbonylpyrrolidine-2-Carboxylic Acid is a high-purity, protected amino acid derivative that serves as a critical building block in advanced organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in the pharmaceutical sector. This compound is essential for researchers and manufacturers in medicinal chemistry, peptide synthesis, and the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used as a protected proline derivative for the solid-phase and solution-phase synthesis of peptides and peptidomimetics.
• Medicinal Chemistry Research: Serves as a versatile building block for constructing combinatorial libraries and exploring structure-activity relationships (SAR).
• Organic Synthesis: Employed in the preparation of chiral catalysts, ligands, and other specialty fine chemicals.
• Bioconjugation: Can be utilized in the development of antibody-drug conjugates (ADCs) and other biopharmaceuticals.

Basic Information

Product Name	1-Phenylmethoxycarbonylpyrrolidine-2-Carboxylic Acid
CAS No.	3160-46-1
Molecular Formula	C14H17NO4
Molecular Weight	263.29 g/mol
Synonyms	N-Cbz-L-Proline; N-Carbobenzoxy-L-proline; (S)-1-[(Benzyloxy)carbonyl]pyrrolidine-2-carboxylic acid; Z-L-Proline; Z-Pro-OH; L-Proline, N-[(phenylmethoxy)carbonyl]-; NSC 3349; Fmoc-Pro-OH (Note: This is a common related compound, often searched alongside)
EINECS	221-619-8

Quality Control

Our 1-Phenylmethoxycarbonylpyrrolidine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, enantiomeric purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.