Description

2-O,3-O,5-O,6-o-Tetramethyl-D-Glucofuranose is a high-purity, protected sugar derivative essential for advanced organic synthesis. This compound serves as a critical chiral building block and protecting group intermediate, enabling the precise construction of complex carbohydrate and nucleoside analogs. It is primarily required by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of nucleoside analogs, antiviral agents, and other active pharmaceutical ingredients (APIs).
• Carbohydrate Chemistry Research: Serves as a vital protected intermediate for the controlled glycosylation and assembly of complex oligosaccharides.
• Agrochemical Synthesis: Used in the development of chiral herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Acts as a building block for specialty surfactants, ligands, and chiral catalysts.
• Glycobiology Studies: Employed in the preparation of standardized probes and substrates for enzymatic and binding studies.
• Process Development: Utilized in scaling up routes to carbohydrate-based therapeutics and diagnostics.

Basic Information

Product Name	2-O,3-O,5-O,6-o-Tetramethyl-D-Glucofuranose
CAS No.	3149-58-4
Molecular Formula	C10H18O6
Molecular Weight	234.25 g/mol
Synonyms	1,2-O-Isopropylidene-3,5,6-tri-O-methyl-α-D-glucofuranose; 3,5,6-Tri-O-methyl-1,2-O-isopropylidene-α-D-glucofuranose; 1,2-O-Isopropylidene-3,5,6-tri-O-methyl-D-glucofuranose; α-D-Glucofuranose, 1,2-O-(1-methylethylidene)-3,5,6-tri-O-methyl-; 3,5,6-Tri-O-methyl-1,2-O-isopropylidene-α-D-glucose; Protected D-Glucose Derivative
EINECS	221-567-9

Quality Control

Our 2-O,3-O,5-O,6-o-Tetramethyl-D-Glucofuranose is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation [α]20/D	-20° to -25° (c=1 in CHCl3)
Melting Point	78°C - 82°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.