Description

Cyclohexanone, 2-Methylene- CAS NO 3045-98-5 is a specialized, reactive ketone derivative characterized by an exocyclic methylene group, making it a valuable synthon in advanced organic synthesis. This compound is crucial for introducing the cyclohexanone framework with an activated site for further functionalization, enabling the construction of complex molecular architectures. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for applications in intermediate synthesis and material science.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing functionalized cyclohexane rings.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where the cyclohexanone core is required.
• Fine Chemical Production: Acts as a precursor for flavors, fragrances, and other specialty chemicals requiring specific ketone functionalities.
• Polymer & Material Science: Employed as a monomer or cross-linking agent in the development of specialty polymers and resins.
• Organic Synthesis Reagent: Utilized in Diels-Alder reactions, Michael additions, and other carbon-carbon bond-forming transformations in research laboratories.
• Chemical Research: Provides a versatile scaffold for medicinal chemistry and drug discovery programs targeting various disease pathways.

Basic Information

Product Name	Cyclohexanone, 2-Methylene-
CAS No.	3045-98-5
Molecular Formula	C7H10O
Molecular Weight	110.15 g/mol
Synonyms	2-Methylenecyclohexanone; 2-Methylidenecyclohexanone; Cyclohexanone, 2-methylene-; 2-Methylene-cyclohexanone; NSC 406079; 2-Methylen-cyclohexanon; α-Methylenecyclohexanone; 2-Methylen-cyclohexanon [German]; 2-Methylène-cyclohexanone [French]
EINECS	221-261-5

Quality Control

Our production of Cyclohexanone, 2-Methylene- adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality systems are designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its reactive nature, isolate from strong oxidizing agents, strong bases, and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.480 - 1.490
Density (g/mL at 20°C)	0.980 - 1.000

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.