Description

3-Nitrophenylacetylene is a versatile aromatic alkyne building block characterized by its nitro-substituted phenyl ring. This compound is essential for advanced organic synthesis, enabling the construction of complex molecular architectures through cross-coupling and cycloaddition reactions. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and materials science sectors for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those containing complex heterocyclic or conjugated systems.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its reactivity to create novel bioactive molecules.
• Material Science Research: Serves as a monomer or building block for creating advanced polymers, liquid crystals, and organic electronic materials.
• Organic Synthesis Reagent: Employed in Sonogashira coupling, Huisgen cycloaddition (click chemistry), and other palladium-catalyzed reactions to form carbon-carbon bonds.
• Chemical Research & Development: A fundamental reagent in academic and industrial labs for exploring new synthetic methodologies and constructing molecular libraries.
• Dye and Pigment Intermediate: Used in the synthesis of specialized dyes and pigments where the nitro and alkyne functionalities contribute to color and properties.

Basic Information

Product Name	3-Nitrophenylacetylene
CAS No.	3034-94-4
Molecular Formula	C8H5NO2
Molecular Weight	147.13 g/mol
Synonyms	3-Nitrophenylacetylene; 1-Ethynyl-3-nitrobenzene; m-Nitrophenylacetylene; 3-Nitrobenzeneacetylene; 3-Nitrophenylethyne; 3-Nitro-1-ethynylbenzene; (3-Nitrophenyl)acetylene; m-Nitrophenylethyne
EINECS	221-228-9

Quality Control

Our 3-Nitrophenylacetylene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, the container should be opaque or stored in a dark cabinet.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	64 - 68 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.