Description

N,N'-Diacetylglycine Anhydride is a high-purity chemical intermediate primarily used in advanced organic synthesis. This compound is valued for its role as a versatile building block in the preparation of peptides, heterocycles, and other complex molecular architectures. It is essential for research and development laboratories, pharmaceutical synthesis, and fine chemical manufacturing requiring precise and reliable starting materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Peptide Chemistry: Serves as a protected glycine derivative or a coupling agent in peptide synthesis protocols.
• Heterocyclic Compound Synthesis: Used in the construction of various nitrogen-containing heterocycles, which are common scaffolds in medicinal chemistry.
• Bioconjugation & Linker Chemistry: Utilized in the development of chemical probes, bioconjugates, and cleavable linkers for drug delivery systems.
• Academic & Industrial R&D: A valuable reagent for method development and exploratory research in organic and bioorganic chemistry.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals and advanced materials.

Basic Information

Product Name	N,N'-Diacetylglycine Anhydride
CAS No.	3027-05-2
Molecular Formula	C6H7NO4
Molecular Weight	157.13 g/mol
Synonyms	2,5-Dioxo-1,4-diacetylpiperazine; Diacetylglycine Anhydride; 1,4-Diacetyl-2,5-piperazinedione; N,N'-Diacetylpiperazine-2,5-dione; Glycine, N,N'-diacetyl-, anhydride; Acetic acid, anhydride with iminodiacetic acid; 1,4-Diacetylpiperazine-2,5-dione; 2,5-Piperazinedione, 1,4-diacetyl-
EINECS	221-185-9

Quality Control

Our N,N'-Diacetylglycine Anhydride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using validated methods including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed immediately after use to prevent degradation due to moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	185 - 190 °C
Loss on Drying	≤ 1.0 %
Residue on Ignition	≤ 0.1 %
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.