Description

(2-Fluorobenzyl)Methylamine is a versatile fluorinated aromatic amine building block of significant interest in advanced organic synthesis. Its value lies in the strategic combination of a reactive primary amine group and a fluorine-substituted benzyl moiety, enabling precise molecular modifications. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of complex fluorinated fine chemicals and specialty materials.
• Research & Development: A valuable reagent for medicinal chemistry and process chemistry research in both academic and industrial laboratories.
• Chemical Biology Probes: Can be utilized to develop molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	(2-Fluorobenzyl)Methylamine
CAS No.	399-30-4
Molecular Formula	C8H10FN
Molecular Weight	139.17 g/mol
Synonyms	1-(2-Fluorophenyl)-N-methylmethanamine; N-Methyl-1-(2-fluorophenyl)methanamine; N-Methyl(2-fluorobenzyl)amine; 2-Fluorobenzylmethylamine; N-Methyl-2-fluorobenzylamine; (2-Fluorophenyl)-N-methylmethanamine; α-(Methylamino)-2-fluorotoluene
EINECS	Contact for details

Quality Control

Our (2-Fluorobenzyl)Methylamine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to support cGMP compliance for pharmaceutical applications, and we welcome audits to ensure we meet your stringent supply chain requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is easily oxidized; prolonged exposure to air should be avoided. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.