Description

n-(5-Chloro-2-Fluorophenyl)Acetamide is a high-purity, halogenated acetamide derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific substitution pattern enables precise molecular modifications. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality intermediates for complex synthesis pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development and production of advanced herbicides and pesticides, where the chloro-fluoro aromatic system contributes to biological activity.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, amide bond formations, and as a scaffold for constructing more complex heterocyclic compounds in research laboratories.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and impurity profiling in related chemical processes.

Basic Information

Product Name	n-(5-Chloro-2-Fluorophenyl)Acetamide
CAS No.	398-89-0
Molecular Formula	C8H7ClFNO
Molecular Weight	187.60 g/mol
Synonyms	N-Acetyl-5-chloro-2-fluoroaniline; 5'-Chloro-2'-fluoroacetanilide; 1-Acetamido-5-chloro-2-fluorobenzene; 2-Fluoro-5-chloroacetanilide; Acetamide, N-(5-chloro-2-fluorophenyl)-; 398-89-0; 5-Chloro-2-fluoroacetanilide; N-(5-Chloro-2-fluorophenyl)acetamide
EINECS	Contact for details

Quality Control

Our n-(5-Chloro-2-Fluorophenyl)Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for synthetic intermediates. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	142 - 147 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.