Description

4-Chloro-4'-Fluorobiphenyl is a high-purity halogenated biphenyl derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which provides a versatile scaffold for creating complex molecules in research and industrial applications. This compound is essential for pharmaceutical R&D, agrochemical development, and the production of specialty materials such as liquid crystals and polymers.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for compounds requiring a halogenated biphenyl core.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of liquid crystal displays (LCDs) and other electronic materials.
• Polymer & Material Science: Acts as a monomer or additive for creating high-performance polymers with specific thermal or optical properties.
• Organic Light-Emitting Diodes (OLEDs): Investigated as a component in the development of novel electroluminescent materials.
• Chemical Research: A valuable reagent in cross-coupling reactions (e.g., Suzuki, Heck) and other catalytic processes in academic and industrial laboratories.

Basic Information

Product Name	4-Chloro-4'-Fluorobiphenyl
CAS No.	398-22-1
Molecular Formula	C12H8ClF
Molecular Weight	206.64 g/mol
Synonyms	4-Chloro-4'-fluorobiphenyl; 1-Chloro-4-(4-fluorophenyl)benzene; 4-Fluoro-4'-chlorobiphenyl; p-Chloro-p'-fluorobiphenyl; 4-Chloro-4'-fluorodiphenyl; (4-Chlorophenyl)(4-fluorophenyl); Biphenyl, 4-chloro-4'-fluoro-; 398-22-1
EINECS	206-924-5

Quality Control

Our 4-Chloro-4'-Fluorobiphenyl is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee compliance with your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	85 - 89 °C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.