Description

4-Bromo-4'-Fluorobiphenyl is a high-purity biphenyl derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its halogenated aromatic structure, which provides specific reactivity for constructing complex molecular architectures. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and materials science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the biphenyl core contributes to biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated liquid crystal compounds and organic light-emitting diode (OLED) materials for electronic displays.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers with enhanced thermal and chemical resistance.
• Organic Synthesis Building Block: Employed in Suzuki-Miyaura and other cross-coupling reactions to create more complex, functionalized biphenyl systems.
• Chemical Research: Used in academic and industrial laboratories for methodological studies in catalysis and synthetic organic chemistry.

Basic Information

Product Name	4-Bromo-4'-Fluorobiphenyl
CAS No.	398-21-0
Molecular Formula	C₁₂H₈BrF
Molecular Weight	251.09 g/mol
Synonyms	4-Bromo-4'-fluorobiphenyl; 4'-Fluoro-4-bromobiphenyl; 1-Bromo-4-(4-fluorophenyl)benzene; p-Bromo-p'-fluorobiphenyl; [1,1'-Biphenyl]-4-bromo-4'-fluoro-; 398-21-0; 4-Fluoro-4'-bromobiphenyl
EINECS	Contact for details

Quality Control

Our 4-Bromo-4'-Fluorobiphenyl is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	108°C - 112°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.