Description

2-Acetamido-4-Fluoroanisole is a high-purity fluorinated aniline derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in providing a versatile, functionalized aromatic scaffold for constructing complex molecules, particularly in the pharmaceutical sector. This compound is essential for research chemists and manufacturers developing new active pharmaceutical ingredients (APIs), agrochemicals, and specialty dyes.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in fluorinated compound libraries targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and stability.
• Material Science Research: Acts as a monomer or precursor for specialty polymers and liquid crystals, leveraging its aromatic and amide functionalities.
• Dye and Pigment Manufacturing: Intermediate for producing high-performance, light-fast fluorinated dyes and pigments.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D in cross-coupling reactions and heterocycle formation.

Basic Information

Product Name	2-Acetamido-4-Fluoroanisole
CAS No.	397-34-2
Molecular Formula	C9H10FNO2
Molecular Weight	183.18 g/mol
Synonyms	N-(4-Fluoro-2-methoxyphenyl)acetamide; 4'-Fluoro-2'-methoxyacetanilide; 2-Acetamido-4-fluoroanisole; 1-Acetamido-4-fluoro-2-methoxybenzene; 4-Fluoro-2-methoxyacetanilide; Acetamide, N-(4-fluoro-2-methoxyphenyl)-; 2-Methoxy-4-fluoroacetanilide
EINECS	Contact for details

Quality Control

Our 2-Acetamido-4-Fluoroanisole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	108°C - 112°C
Loss on Drying	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.