Description

6-Fluoroquinoline is a versatile fluorinated heterocyclic building block essential for advanced organic synthesis. Its core value lies in the strategic introduction of a fluorine atom onto the quinoline scaffold, which can dramatically alter the electronic properties, metabolic stability, and bioavailability of target molecules. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated quinolone antibiotics and other bioactive molecules where the fluorine atom enhances potency.
• Agrochemical Synthesis: Used in developing new generations of herbicides, fungicides, and pesticides with improved efficacy and environmental profiles.
• Material Science Research: Serves as a building block for creating organic semiconductors, liquid crystals, and fluorescent dyes due to its electron-deficient aromatic system.
• Chemical Biology & Proteomics: Employed as a tagging reagent or a core structure for designing molecular probes and enzyme inhibitors.
• Catalyst Ligand Development: The nitrogen and fluorine atoms make it a candidate for designing novel ligands in transition metal catalysis.
• Academic & Contract Research: A valuable reagent for methodological studies in cross-coupling reactions and C-H functionalization.

Basic Information

Product Name	6-Fluoroquinoline
CAS No.	396-30-5
Molecular Formula	C9H6FN
Molecular Weight	147.15 g/mol
Synonyms	Quinoline, 6-fluoro-; 6-Fluoro-quinoline; 6-Fluorochinolin; NSC 404058; 6-Fluorochinoline; 6-Fluoro-1-azanaphthalene; 6-Fluoro-benzo[b]pyridine
EINECS	Contact for details

Quality Control

Our 6-Fluoroquinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, purity, and impurity profiles to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.