Description

4-Fluoroquinoline is a versatile fluorinated heterocyclic building block essential for advanced organic synthesis and pharmaceutical research. This compound is valued for its ability to introduce the quinoline scaffold with a fluorine substituent, which can significantly alter the biological activity, metabolic stability, and physicochemical properties of target molecules. It is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in antimicrobial, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances bioactivity and environmental persistence.
• Material Science Precursor: Serves as a building block for creating organic electronic materials, ligands for catalysis, and fluorescent dyes or probes.
• Chemical Research & Development: Employed in academic and industrial R&D for method development, structure-activity relationship (SAR) studies, and exploring new fluorination chemistries.
• Ligand Synthesis: Useful for preparing complex ligands used in coordination chemistry and homogeneous catalysis.

Basic Information

Product Name	4-Fluoroquinoline
CAS No.	394-70-7
Molecular Formula	C9H6FN
Molecular Weight	147.15 g/mol
Synonyms	Quinoline, 4-fluoro-; 4-Fluoro-quinoline; 4-Fluorochinolin; NSC 404087; 4-Fluorquinolin; Fluorquinoline; 4-FQ
EINECS	206-907-6

Quality Control

Every batch of our 4-Fluoroquinoline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, supporting your regulatory and research requirements. A Certificate of Analysis (COA) detailing specifications such as assay (by HPLC), identity (by IR/NMR), and impurity profile is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.