Description

5-Fluoro Quinoline is a versatile fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters as a key intermediate for introducing the quinoline scaffold with a fluorine substituent, enabling the development of novel compounds with enhanced biological activity and physicochemical properties. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, particularly for antiviral, anticancer, and anti-inflammatory applications.
• Agrochemical Research: Used to develop novel pesticides and herbicides where the fluorine atom improves metabolic stability and bioavailability.
• Material Science: Serves as a building block for creating functional organic materials, such as ligands for catalysts and components for organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Employed in cross-coupling reactions and as a scaffold for constructing more complex heterocyclic systems in medicinal chemistry.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research into the effects of fluorination on molecular properties and reactivity.

Basic Information

Product Name	5-Fluoro Quinoline
CAS No.	394-69-4
Molecular Formula	C9H6FN
Molecular Weight	147.15 g/mol
Synonyms	5-Fluoroquinoline; Quinoline, 5-fluoro-; 5-Fluorochinolin; 5-Fluoro-1-azanaphthalene; 5-Fluoro-lepidine; 394-69-4; 5-Fluorochinoline; NSC 406918
EINECS	206-905-8

Quality Control

Our 5-Fluoro Quinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, GC, and NMR, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials and sources of ignition.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.