Description

2-Amino-4-Nitrobenzotrifluoride is a high-value aromatic nitroamine derivative containing a trifluoromethyl group, serving as a critical building block in advanced organic synthesis. Its unique structure, combining electron-withdrawing nitro and trifluoromethyl groups with an electron-donating amino group, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by the pharmaceutical, agrochemical, and specialty chemical industries for the development of active ingredients, dyes, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a trifluoromethylated aromatic core.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl group enhances biological activity and stability.
• Dye and Pigment Manufacturing: Serves as a starting material for producing high-performance azo dyes and organic pigments with superior color fastness.
• Liquid Crystal and OLED Material Research: Acts as a building block for electron-transport materials and other functional components in electronic displays.
• Polymer Modification: Employed to introduce fluorinated aromatic units into polymer chains, improving chemical resistance and thermal stability.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D in medicinal chemistry and material science.

Basic Information

Product Name	2-Amino-4-Nitrobenzotrifluoride
CAS No.	393-49-7
Molecular Formula	C7H5F3N2O2
Molecular Weight	206.12 g/mol
Synonyms	4-Nitro-2-(trifluoromethyl)aniline; 2-Amino-α,α,α-trifluoro-p-nitrotoluene; 2-Trifluoromethyl-4-nitroaniline; 2-CF3-4-NO2-Aniline; Benzenamine, 4-nitro-2-(trifluoromethyl)-; α,α,α-Trifluoro-4-nitro-o-toluidine
EINECS	206-889-6

Quality Control

Our 2-Amino-4-Nitrobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and spectroscopic identification (IR, NMR). We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider an inert atmosphere (e.g., nitrogen or argon) to maintain stability. Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.