Description

2-Fluoromandelic Acid is a fluorinated derivative of mandelic acid, serving as a versatile chiral building block and intermediate in advanced organic synthesis. Its value lies in the introduction of a fluorine atom, which can significantly alter the biological activity, metabolic stability, and physicochemical properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of fluorinated drug candidates, including potential enzyme inhibitors and receptor modulators.
• Agrochemical Research: Used to develop novel fluorinated pesticides and herbicides, where the fluorine atom enhances bioactivity and environmental persistence.
• Asymmetric Synthesis: Employed as a resolving agent or chiral auxiliary in the preparation of enantiomerically pure compounds.
• Biochemical Studies: Utilized as a probe or substrate in enzymatic studies to investigate fluorination effects on metabolic pathways.
• Material Science: Potential monomer or additive in the development of specialized polymers with unique properties.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in chemical production.

Basic Information

Product Name	2-Fluoromandelic Acid
CAS No.	389-31-1
Molecular Formula	C8H7FO3
Molecular Weight	170.14 g/mol
Synonyms	(2-Fluorophenyl)glycolic Acid; α-Hydroxy-2-fluorophenylacetic Acid; 2-Fluorobenzene glycolic Acid; DL-2-Fluoromandelic Acid; (±)-2-Fluoromandelic Acid; 2-Fluoro-α-hydroxybenzeneacetic Acid; 2-Fluorophenylhydroxyacetic Acid; Mandelic acid, 2-fluoro-
EINECS	206-867-6

Quality Control

Our 2-Fluoromandelic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for research and synthesis. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality commitment ensures reliable performance and traceability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.