Description

1-[2-(Trifluoromethyl)Phenyl]Hydrazine is a specialized aromatic hydrazine derivative featuring a trifluoromethyl substituent, which imparts unique electronic and steric properties. This compound is a critical pharmaceutical intermediate and organic synthesis building block, valued for its role in constructing nitrogen-containing heterocycles and active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various heterocyclic compounds, including pyrazoles and indazoles, which are core structures in many drug candidates.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging the biological activity of the hydrazine moiety.
• Dye and Pigment Manufacturing: Serves as a coupling agent in the production of azo dyes and specialty colorants.
• Chemical Research & Development: A versatile reagent for organic synthesis, particularly in reactions involving nucleophilic substitution and cyclization.
• Material Science: Potential building block for advanced polymers and liquid crystal materials due to its aromatic and fluorinated structure.
• Analytical Chemistry: Can be used as a derivatization agent for the detection and analysis of carbonyl compounds.

Basic Information

Product Name	1-[2-(Trifluoromethyl)Phenyl]Hydrazine
CAS No.	365-34-4
Molecular Formula	C7H7F3N2
Molecular Weight	176.14 g/mol
Synonyms	(2-(Trifluoromethyl)phenyl)hydrazine; 2-(Trifluoromethyl)phenylhydrazine; 1-Hydrazino-2-(trifluoromethyl)benzene; α,α,α-Trifluoro-o-tolylhydrazine; o-Trifluoromethylphenylhydrazine; 2-Trifluoromethylphenylhydrazine; Hydrazine, [2-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 1-[2-(Trifluoromethyl)Phenyl]Hydrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We can supply material compliant with various pharmacopeial standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.