Description

2-Hydroxymethyl-5-Trifluoromethyl-Phenol is a versatile trifluoromethylated phenolic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a hydroxymethyl and a strongly electron-withdrawing trifluoromethyl group, makes it a valuable intermediate for creating molecules with enhanced properties. This compound is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in areas requiring fluorinated molecules for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies.
• Polymer Modification: Employed to introduce phenolic and fluorinated functionalities into polymers, altering their surface properties, chemical resistance, and thermal stability.
• Organic Synthesis Reagent: Utilized in various organic transformations, including etherification, esterification, and as a protecting group scaffold.
• Research & Development: Essential compound for academic and industrial R&D exploring the effects of fluorination on material and biological properties.

Basic Information

Product Name	2-Hydroxymethyl-5-Trifluoromethyl-Phenol
CAS No.	349-66-6
Molecular Formula	C8H7F3O2
Molecular Weight	192.14 g/mol
Synonyms	5-(Trifluoromethyl)salicyl alcohol; 2-(Hydroxymethyl)-4-(trifluoromethyl)phenol; (2-Hydroxy-5-trifluoromethylphenyl)methanol; α-Hydroxy-5-trifluoromethyl-o-cresol; 2-Hydroxymethyl-α,α,α-trifluoro-p-cresol; 5-Trifluoromethylsalicyl alcohol; 2-Hydroxymethyl-4-trifluoromethylphenol
EINECS	Contact for details

Quality Control

Our 2-Hydroxymethyl-5-Trifluoromethyl-Phenol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which may affect product quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.