Description

3-Nitro-5-(Trifluoromethyl)Phenol is a versatile aromatic intermediate characterized by its nitro and trifluoromethyl substituents, which confer unique electronic and steric properties. This compound is essential for the synthesis of advanced materials and active pharmaceutical ingredients (APIs) where structural fine-tuning is critical. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for building complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for electron-deficient components in electronic display materials and organic light-emitting diodes (OLEDs).
• Dye & Pigment Manufacturing: Intermediate for producing high-performance, light-fast azo dyes and pigments.
• Polymer Modification: Functional monomer for creating specialty polymers with tailored thermal and chemical resistance properties.
• Chemical Research & Development: Valuable reagent in academic and industrial labs for exploring new organic reactions and catalysis.

Basic Information

Product Name	3-Nitro-5-(Trifluoromethyl)Phenol
CAS No.	349-57-5
Molecular Formula	C7H4F3NO3
Molecular Weight	207.11 g/mol
Synonyms	5-(Trifluoromethyl)-3-nitrophenol; 3-Nitro-α,α,α-trifluoro-m-cresol; 3-Nitro-5-trifluoromethylphenol; 2-Hydroxy-5-nitrobenzotrifluoride; Phenol, 3-nitro-5-(trifluoromethyl)-; m-Nitro-α,α,α-trifluoro-m-cresol; 3-Nitro-5-(trifluoromethyl)benzenol
EINECS	206-497-5

Quality Control

Our 3-Nitro-5-(Trifluoromethyl)Phenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.