Description

2-Heptyl-4-Hydroxyquinoline n-Oxide is a specialized quinoline derivative, recognized for its role as a potent and specific inhibitor of the mitochondrial electron transport chain. This compound matters for researchers and industrial chemists requiring precise biochemical modulation, particularly in studies of cellular respiration and energy metabolism. It is needed by professionals in the pharmaceutical, agrochemical, and life science research sectors for developing novel therapeutic agents, biocides, and as a critical biochemical tool.

Application

• Biochemical Research: As a specific inhibitor of mitochondrial Complex I (NADH:ubiquinone oxidoreductase), used to study respiratory pathways, oxidative stress, and energy metabolism in cell biology.
• Pharmaceutical Intermediates: Serves as a key synthetic building block or precursor in the development of novel antimicrobial and antiparasitic agents.
• Agrochemical Development: Investigated for its potential use in creating new fungicides or bactericides due to its mode of action on biological energy systems.
• Microbiological Studies: Used in laboratory settings to selectively inhibit bacterial growth for research purposes, particularly against certain Gram-negative bacteria.
• Enzyme Inhibition Studies: A tool compound for probing the activity and mechanism of NADH-dehydrogenase and related enzymes in vitro.

Basic Information

Product Name	2-Heptyl-4-Hydroxyquinoline n-Oxide
CAS No.	341-88-8
Molecular Formula	C₁₆H₂₁NO₂
Molecular Weight	259.35 g/mol
Synonyms	2-Heptyl-4-hydroxyquinoline 1-oxide; HQNO; Heptylhydroxyquinoline-N-oxide; 4-Hydroxy-2-heptylquinoline N-oxide; 2-Heptyl-4-hydroxyquinoline N-oxide; 2-n-Heptyl-4-hydroxyquinoline N-oxide; 1-Hydroxy-2-heptyl-4(1H)-quinolinone; Antibiotic HQNO
EINECS	206-433-5

Quality Control

Our 2-Heptyl-4-Hydroxyquinoline n-Oxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay (HPLC), related substances, and physical characteristics. Our quality commitment supports applications in research and development where reliable and traceable materials are essential.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.