Description

1-Bromo-4-Fluoronaphthalene is a high-purity halogenated naphthalene derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique reactivity, where the bromine and fluorine substituents offer distinct sites for selective cross-coupling and functionalization reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors, particularly for developing novel active ingredients and functional organic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially those requiring fluorinated or brominated aromatic systems for enhanced bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides, where the naphthalene core provides a robust scaffold for active ingredients.
• Organic Light-Emitting Diodes (OLEDs): Acts as a starting material for synthesizing electron-transport or host materials in OLED displays and lighting due to its fused aromatic structure.
• Liquid Crystal & Electronic Materials: Employed in the development of fluorinated liquid crystals and other electronic chemicals for display technologies.
• Cross-Coupling Reactions: Serves as a versatile substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct biaryl systems.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Product Name	1-Bromo-4-Fluoronaphthalene
CAS No.	341-41-3
Molecular Formula	C10H6BrF
Molecular Weight	225.06 g/mol
Synonyms	4-Fluoro-1-bromonaphthalene; 1-Bromo-4-fluoronaphthalene; Naphthalene, 1-bromo-4-fluoro-; 4-Bromo-1-fluoronaphthalene (registry number check required); 1-Fluoro-4-bromonaphthalene
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Fluoronaphthalene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or otherwise opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.