Description

4-(Trifluoromethyl)Benzhydrazide is a high-purity, versatile aromatic hydrazide derivative characterized by its trifluoromethyl functional group. This compound serves as a critical pharmaceutical intermediate and organic synthesis building block, valued for its ability to introduce the trifluoromethyl moiety into target molecules, thereby modulating their physicochemical properties. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring the bioisosteric trifluoromethyl group for enhanced metabolic stability and lipophilicity.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides where the CF3 group improves efficacy and environmental profile.
• Ligand and Catalyst Preparation: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and other synthetic transformations.
• Heterocyclic Chemistry: Essential starting material for the construction of various nitrogen-containing heterocycles, such as pyrazoles and triazoles, with applications in medicinal and material chemistry.
• Polymer Modification: Serves as a functional monomer or cross-linking agent for introducing specific properties into polymeric materials.
• Research & Development: A valuable tool compound in academic and industrial R&D for exploring new synthetic pathways and structure-activity relationships.

Basic Information

Product Name	4-(Trifluoromethyl)Benzhydrazide
CAS No.	339-59-3
Molecular Formula	C8H7F3N2O
Molecular Weight	204.15 g/mol
Synonyms	p-(Trifluoromethyl)benzhydrazide; 4-(Trifluoromethyl)benzohydrazide; α,α,α-Trifluoro-p-toluhydrazide; Benzoic acid, 4-(trifluoromethyl)-, hydrazide; 4-Trifluoromethylbenzoylhydrazine; 4-CF3-Benzhydrazide; 4-Trifluoromethylbenzhydrazide; (4-Trifluoromethylphenyl)formic acid hydrazide
EINECS	206-417-4

Quality Control

Our 4-(Trifluoromethyl)Benzhydrazide is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure it meets the highest standards of purity and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing key parameters such as assay, identity, and impurity profiles. We are committed to supplying material that supports your GMP and ISO-aligned processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.