Description

2-Chloro-n-(2-Chloro-5-Trifluoromethyl-Phenyl)-Acetamide is a specialized halogenated acetamide derivative with a trifluoromethylphenyl group, offering unique reactivity and physicochemical properties. This compound is valued as a critical chemical intermediate in advanced organic synthesis, particularly for constructing complex molecules with specific halogen and fluorine substitutions. It is primarily needed by pharmaceutical and agrochemical research and development teams for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the trifluoromethyl and chloro groups contribute to biological activity and environmental persistence.
• Organic Synthesis Reagent: Serves as a versatile electrophile or amide precursor in academic and industrial laboratories for constructing complex heterocycles and functionalized aromatic systems.
• Material Science Research: Investigated as a monomer or additive precursor for specialty polymers and coatings, leveraging its halogenated structure for flame retardancy or specific surface properties.
• Chemical Biology Probe Development: Utilized in creating molecular probes and tags for studying biological processes, where its distinct structure can be used for labeling or as a pharmacophore.

Basic Information

Product Name	2-Chloro-n-(2-Chloro-5-Trifluoromethyl-Phenyl)-Acetamide
CAS No.	328-26-7
Molecular Formula	C9H6Cl2F3NO
Molecular Weight	272.05 g/mol
Synonyms	N-(2-Chloro-5-(trifluoromethyl)phenyl)-2-chloroacetamide; 2-Chloro-N-[2-chloro-5-(trifluoromethyl)phenyl]acetamide; α-Chloro-2-chloro-α,α,α-trifluoro-p-acetotoluidide; 2-Chloroacet-2'-chloro-5'-(trifluoromethyl)anilide; Acetamide, 2-chloro-N-[2-chloro-5-(trifluoromethyl)phenyl]-; 328-26-7; 2-Chloro-N-(2-chloro-α,α,α-trifluoro-p-tolyl)acetamide
EINECS	Contact for details

Quality Control

Our 2-Chloro-n-(2-Chloro-5-Trifluoromethyl-Phenyl)-Acetamide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports your R&D and scale-up processes with reliable, traceable material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	142 - 147 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.