Description

8-Trifluoromethylquinoline is a versatile fluorinated heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring a quinoline core substituted with a trifluoromethyl group, provides valuable electronic and steric properties for modulating the activity of target molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients with enhanced efficacy and stability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the trifluoromethyl group can improve biological activity and environmental stability.
• Material Science: Employed in the synthesis of functional organic materials, such as organic light-emitting diodes (OLEDs) and liquid crystals, due to its electron-withdrawing characteristics.
• Coordination Chemistry: Acts as a ligand precursor for creating metal-organic frameworks (MOFs) and catalysts used in specialized chemical transformations.
• Chemical Research: Serves as a standard or reference compound in analytical chemistry and method development for fluorinated compound analysis.

Basic Information

Product Name	8-Trifluoromethylquinoline
CAS No.	317-57-7
Molecular Formula	C10H6F3N
Molecular Weight	197.16 g/mol
Synonyms	Quinoline, 8-(trifluoromethyl)-; 8-(Trifluoromethyl)quinoline; 8-Trifluoromethyl-chinolin; α,α,α-Trifluoro-8-quinolylmethane; 8-CF3-Quinoline; 8-TFMQ
EINECS	206-267-5

Quality Control

Our 8-Trifluoromethylquinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay determination and GC for residual solvent analysis, to meet the stringent requirements of our global clientele. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.