Description

1-Bromo-4-[(trifluoromethyl)sulfonyl]benzene is a versatile and high-value organofluorine building block. This compound matters for its unique combination of a reactive bromoarene handle and a strongly electron-withdrawing triflyl group, enabling precise synthesis in advanced chemical development. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials industries for constructing complex molecules and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring sulfonamide or aryl fluoride motifs.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the trifluoromethanesulfonyl group enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for sophisticated ligands in transition metal catalysis and organocatalysis.
• Material Science: Employed in the production of advanced polymers, liquid crystals, and electronic materials for its electron-accepting properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Sonogashira, and Buchwald-Hartwig amination reactions due to the bromine substituent.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new organic transformations and reaction mechanisms.

Basic Information

Product Name	1-Bromo-4-[(trifluoromethyl)sulfonyl]benzene
CAS No.	312-20-9
Molecular Formula	C7H4BrF3O2S
Molecular Weight	289.07 g/mol
Synonyms	4-Bromophenyl trifluoromethyl sulfone; p-Bromophenyl trifluoromethyl sulfone; 1-Bromo-4-(trifluoromethylsulfonyl)benzene; α,α,α-Trifluoro-4-bromobenzenesulfonamide; (4-Bromophenyl)(trifluoromethyl)sulfone; 4-Bromo-α,α,α-trifluorobenzenesulfonamide; 4-Bromobenzene triflone
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-[(trifluoromethyl)sulfonyl]benzene is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.