Description

Bicyclo[1.1.1]pentane (CAS NO 311-75-1) is a highly strained, rigid organic cage compound that serves as a unique and valuable building block in advanced chemical synthesis. Its exceptional structural properties make it a critical component for developing novel pharmaceuticals, agrochemicals, and advanced materials. This compound is primarily sought by research institutions and industrial R&D departments focused on medicinal chemistry, polymer science, and materials engineering.

Application

• Pharmaceutical Intermediate: Used as a rigid, three-dimensional bioisostere for benzene or tert-butyl groups in drug discovery to improve metabolic stability, solubility, and potency.
• Agrochemical Synthesis: Employed in the development of new active ingredients with enhanced efficacy and environmental profiles.
• Advanced Material Precursor: Serves as a core unit for synthesizing high-performance polymers, liquid crystals, and porous organic frameworks.
• Ligand and Catalyst Development: Utilized to create novel, sterically demanding ligands for catalysis and asymmetric synthesis.
• Academic and Industrial Research: A key reagent for studying strain-release chemistry and developing new synthetic methodologies.
• Cross-Coupling Reactions: Acts as a versatile substrate in Pd-catalyzed and other metal-mediated coupling reactions to introduce the bicyclopentyl moiety.

Basic Information

Product Name	Bicyclo[1.1.1]pentane
CAS No.	311-75-1
Molecular Formula	C5H8
Molecular Weight	68.12 g/mol
Synonyms	[1.1.1]Propellane; Tricyclo[1.1.1.01,3]pentane; Pentacyclo[4.1.0.02,4.03,5.03,5]heptane; BCP; 1,3-Dehydro-5-methylidenebicyclo[2.1.0]pentane
EINECS	206-235-9

Quality Control

Our Bicyclo[1.1.1]pentane is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles as determined by GC, GC-MS, and NMR. Our quality system is designed to meet the stringent requirements of pharmaceutical and advanced material research.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature, store in a cool, well-ventilated place, ideally at 2-8°C or as specified on the label. Keep away from heat, sparks, and open flames. For long-term storage under an inert atmosphere (e.g., argon or nitrogen), please contact us for specific handling recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.