Description

(R)-1,4-Dioxadispiro[4.0.56.45]Pentadecan-7-One is a high-purity, advanced chiral building block characterized by its unique spirocyclic and dioxane-containing structure. This compound is of significant value in organic synthesis, particularly for introducing complex, three-dimensional molecular frameworks with precise stereochemistry. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, catalyst development, and the synthesis of novel materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Catalyst Ligand Precursor: Used in the development of novel chiral ligands for transition metal catalysis, enabling enantioselective synthesis.
• Agrochemical Research: Employed in the synthesis of novel, stereochemically defined bioactive compounds for crop protection.
• Material Science: Acts as a building block for creating specialized polymers or organic frameworks with tailored properties.
• Academic & Industrial R&D: Utilized in methodological studies and exploratory chemistry to access complex molecular architectures.

Basic Information

Product Name	(R)-1,4-Dioxadispiro[4.0.56.45]Pentadecan-7-One
CAS No.	2936670-84-5
Molecular Formula	C14H22O3
Molecular Weight	238.32 g/mol
Synonyms	(7R)-1,4-Dioxadispiro[4.0.56.45]pentadecan-7-one; (R)-1,4-Dioxa-6-azadispiro[4.0.56.45]pentadecan-7-one (related IUPAC); Spiro[dioxolane-2,6'-bicyclo[3.3.1]nonan]-7'-one, (R)-; Chiral Spiroketal; Advanced Bicyclic Building Block
EINECS	Contact for details

Quality Control

Our (R)-1,4-Dioxadispiro[4.0.56.45]Pentadecan-7-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity (typically by HPLC or GC), chiral purity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.