Description

(R)-2-(4-Bromophenyl)Pyrrolidine Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate. This compound is valued for its role in the synthesis of enantiomerically pure molecules, particularly in medicinal chemistry and drug discovery. It is primarily needed by research institutions and pharmaceutical companies developing novel therapeutics, especially those targeting central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug candidates.
• Asymmetric Synthesis: Serves as a chiral auxiliary or precursor in stereoselective chemical transformations.
• Ligand and Catalyst Development: Potential building block for creating novel chiral ligands or organocatalysts.
• Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(R)-2-(4-Bromophenyl)Pyrrolidine Hydrochloride
CAS No.	2829281-55-0
Molecular Formula	C10H12BrN•HCl
Molecular Weight	262.57 g/mol (Free base: 226.11 g/mol)
Synonyms	(R)-2-(4-Bromophenyl)pyrrolidine HCl; (R)-2-(p-Bromophenyl)pyrrolidine hydrochloride; (R)-4-Bromo-α-(pyrrolidin-2-yl)benzene hydrochloride; (R)-1-(4-Bromophenyl)-2-pyrrolidinyl hydrochloride; (2R)-2-(4-Bromophenyl)pyrrolidine hydrochloride; (R)-(-)-2-(4-Bromophenyl)pyrrolidine hydrochloride; (R)-2-(4-Bromo-phenyl)-pyrrolidine hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-2-(4-Bromophenyl)Pyrrolidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.