Description

(1S,3R)-3-Aminocyclohexanecarboxylic Acid Hydrochloride is a high-purity chiral building block essential for advanced pharmaceutical synthesis and research. This compound is valued for its defined stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) with specific biological activity. It is primarily needed by pharmaceutical R&D departments, contract research and manufacturing organizations (CROs/CMOs), and academic research institutions focused on medicinal chemistry and peptide science.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel therapeutic compounds, particularly for central nervous system (CNS) and metabolic disorder targets.
• Peptide Modification: Used to introduce constrained, cyclohexane-based amino acid analogs into peptide chains to enhance stability, bioavailability, and receptor selectivity.
• Protease Inhibitor Development: Serves as a core structural component in the design and development of selective enzyme inhibitors.
• Asymmetric Catalysis Research: Employed as a ligand precursor or a chiral auxiliary in the development of new catalytic systems.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying enzyme function and protein-protein interactions.
• Reference Standard: Provides a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	(1S,3R)-3-Aminocyclohexanecarboxylic Acid Hydrochloride
CAS No.	2829279-57-2
Molecular Formula	C7H14ClNO2
Molecular Weight	179.65 g/mol
Synonyms	(1S,3R)-3-Aminocyclohexane-1-carboxylic acid hydrochloride; cis-3-Aminocyclohexanecarboxylic acid hydrochloride (specifying (1S,3R)); 3-Amino-1-cyclohexanecarboxylic acid hydrochloride (cis-); (1S,3R)-3-ACHC HCl; (1S,3R)-ACHC hydrochloride; cis-3-ACHC HCl; Cyclohexane-1-carboxylic acid, 3-amino-, hydrochloride, (1S,3R)-
EINECS	Contact for details

Quality Control

Our (1S,3R)-3-Aminocyclohexanecarboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed immediately after use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% de
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.