Description

Quinoline, 2,2'-[2,2-Bis[(4R)-4,5-Dihydro-4-(Phenylmethyl)-2-Oxazolyl]-1,3-Propanediyl]Bis- is a sophisticated chiral bis(oxazoline) ligand derivative, a critical component in asymmetric synthesis. This compound matters for its ability to induce high enantioselectivity in catalytic reactions, enabling the production of optically pure intermediates. It is primarily needed by research institutions and pharmaceutical companies developing novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Asymmetric Catalysis: As a chiral ligand for transition metals (e.g., Cu, Pd, Zn) in enantioselective C–H activation, cyclopropanation, and Diels-Alder reactions.
• Pharmaceutical Intermediate Synthesis: For the stereocontrolled construction of complex molecular architectures in drug discovery and development pipelines.
• Fine Chemical Production: Enabling the synthesis of high-value, enantiomerically pure agrochemicals, flavors, and fragrances.
• Academic & Industrial Research: Serving as a key reagent in methodological studies for developing new catalytic systems and synthetic methodologies.
• Material Science: Potential use in the development of chiral polymers or frameworks with specific optical properties.

Basic Information

Item	Details
Product Name	Quinoline, 2,2'-[2,2-Bis[(4R)-4,5-Dihydro-4-(Phenylmethyl)-2-Oxazolyl]-1,3-Propanediyl]Bis-
CAS No.	2828433-47-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	2,2'-[2,2-Bis[(4R)-4,5-Dihydro-4-Benzyl-2-Oxazolyl]-1,3-Propanediyl]Bisquinoline; (R,R)-2,2'-[2,2-Bis(4-Benzyl-4,5-dihydrooxazol-2-yl)propane-1,3-diyl]diquinoline; Chiral Bis(oxazoline)-Quinoline Hybrid Ligand; (R,R)-QuinBOX Derivative; Asymmetric Quinoline-Oxazoline Ligand; (R,R)-2,2'-(2,2-Bis((R)-4-Benzyl-4,5-dihydrooxazol-2-yl)propane-1,3-diyl)diquinoline
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized to confirm identity, chiral purity, and chemical purity, supporting reproducible results in sensitive catalytic applications. Certificates of Analysis (COA) detailing specifications such as enantiomeric excess (ee) and assay are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.