Description

(R)-2-(Piperidin-2-Yl)Pyridine Dihydrochloride is a high-purity chiral building block and pharmaceutical intermediate. This compound is of significant value for the research and development of novel active pharmaceutical ingredients (APIs), particularly in the fields of neurology and oncology. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the development of new therapeutic agents.
• Asymmetric Synthesis: Serves as a chiral ligand or building block in catalytic and stoichiometric asymmetric reactions.
• Neurological Drug Development: Potential intermediate for compounds targeting neurotransmitter receptors and neurological pathways.
• Oncology Research: Utilized in the synthesis of experimental molecules for cancer treatment research.
• Chemical Biology: Employed as a probe or tool compound for studying biological systems and protein interactions.

Basic Information

Product Name	(R)-2-(Piperidin-2-Yl)Pyridine Dihydrochloride
CAS No.	2771315-93-4
Molecular Formula	C10H16N2·2HCl
Molecular Weight	245.17 g/mol (Free base: 164.25)
Synonyms	(R)-2-(2-Pyridyl)piperidine dihydrochloride; (R)-2-Piperidin-2-ylpyridine dihydrochloride; (R)-2-Pyridin-2-ylpiperidine dihydrochloride; (R)-α-Picolylpiperidine dihydrochloride; (R)-Noranabasine dihydrochloride; (2R)-2-(Pyridin-2-yl)piperidine dihydrochloride; (R)-Enantiomer of 2-(2-Piperidyl)pyridine dihydrochloride
EINECS	Contact for details

Quality Control

Our (R)-2-(Piperidin-2-Yl)Pyridine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.