Description

1,6-Naphthyridin-2(1H)-One, 7-Chloro-8-Fluoro-4-Hydroxy- is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure. This compound is critical for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in synthesizing next-generation drug candidates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in oncology and anti-infective research.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization to create libraries of naphthyridine derivatives for biological screening.
• Research & Development: Used in academic and industrial R&D settings for studying structure-activity relationships (SAR) and developing new pharmacophores.
• Active Pharmaceutical Ingredient (API) Manufacturing: An intermediate in the multi-step synthesis of complex, fluorinated API molecules.
• Biochemical Research: Potential tool compound for investigating enzyme inhibition or receptor binding mechanisms due to its specific halogenated structure.

Basic Information

Product Name	1,6-Naphthyridin-2(1H)-One, 7-Chloro-8-Fluoro-4-Hydroxy-
CAS No.	2763157-75-9
Molecular Formula	C8H4ClFN2O2
Molecular Weight	214.58 g/mol
Synonyms	7-Chloro-8-fluoro-4-hydroxy-1,6-naphthyridin-2(1H)-one; 7-Chloro-8-fluoro-4-hydroxy-1H-1,6-naphthyridin-2-one; 4-Hydroxy-7-chloro-8-fluoro-1,6-naphthyridin-2(1H)-one; 7-Chloro-8-fluoro-4-hydroxy-2-oxo-1,2-dihydro-1,6-naphthyridine; 2763157-75-9; 1,6-Naphthyridin-2-ol, 7-chloro-8-fluoro-4-hydroxy-; Fluorinated Chloro Hydroxy Naphthyridinone
EINECS	Contact for details

Quality Control

Our 1,6-Naphthyridin-2(1H)-One, 7-Chloro-8-Fluoro-4-Hydroxy- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.