Description

Pyridine, 2-[(4R)-4,5-Dihydro-4-(1-Methylethyl)-2-Oxazolyl]-6-Methyl- is a high-purity, chiral oxazoline-substituted pyridine derivative. This compound serves as a versatile and valuable chiral ligand or building block in advanced organic synthesis and catalysis. It is primarily required by pharmaceutical R&D, agrochemical synthesis, and fine chemical manufacturing sectors for the development of enantiomerically pure products.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs) requiring high stereoselectivity.
• Catalytic Ligand: Used in asymmetric synthesis, including hydrogenation, cyclopropanation, and C-H activation reactions, to induce chirality.
• Agrochemical Research: Employed in the development of novel, enantiopure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Synthesis: Acts as a specialized building block for complex molecules in material science and specialty chemistry.
• Academic & Industrial R&D: A valuable tool for chemists exploring new methodologies in asymmetric catalysis and medicinal chemistry.

Basic Information

Product Name	Pyridine, 2-[(4R)-4,5-Dihydro-4-(1-Methylethyl)-2-Oxazolyl]-6-Methyl-
CAS No.	2757083-00-2
Molecular Formula	C12H16N2O
Molecular Weight	204.27 g/mol
Synonyms	(4R)-4-Isopropyl-2-(6-methylpyridin-2-yl)-4,5-dihydrooxazole; (R)-4-Isopropyl-2-(6-methyl-2-pyridyl)-2-oxazoline; 2-[(4R)-4,5-Dihydro-4-isopropyl-2-oxazolyl]-6-methylpyridine; (R)-2-(6-Methylpyridin-2-yl)-4-isopropyl-4,5-dihydrooxazole; Chiral Pyridine-Oxazoline Ligand; (R)-iPr-PyOx
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Quality is verified through advanced analytical techniques including HPLC, chiral GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (ee%), and impurity profile is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (ee%)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.