Description

2,2'-Bipyridine, 6-[(4R)-4,5-Dihydro-4-(1-Methylethyl)-2-Oxazolyl]- is a sophisticated chiral ligand and building block derived from the 2,2'-bipyridine scaffold, featuring a stereogenic center and an oxazoline moiety. This compound is highly valued for its ability to impart enantioselectivity in transition metal-catalyzed reactions, which is critical for the synthesis of optically active intermediates. It is primarily sought after by research and development teams in the pharmaceutical and fine chemical sectors for applications in asymmetric synthesis and catalysis.

Application

• As a chiral ligand in asymmetric transition metal catalysis (e.g., hydrogenation, cross-coupling).
• Building block for the synthesis of novel, complex chiral catalysts and organocatalysts.
• Research tool in medicinal chemistry for the development of enantiomerically pure drug candidates.
• Key intermediate in the preparation of functionalized materials with specific optical properties.
• Use in academic and industrial R&D for method development in stereoselective synthesis.
• Component in catalyst systems for the production of high-value specialty and agrochemicals.

Basic Information

Product Name	2,2'-Bipyridine, 6-[(4R)-4,5-Dihydro-4-(1-Methylethyl)-2-Oxazolyl]-
CAS No.	2757082-46-3
Molecular Formula	C16H19N3O
Molecular Weight	269.34 g/mol
Synonyms	(R)-6-(4-Isopropyl-4,5-dihydrooxazol-2-yl)-2,2'-bipyridine; (R)-2-(6-(2,2'-Bipyridin-6-yl)-4-isopropyl-4,5-dihydrooxazole; 6-[(4R)-4,5-Dihydro-4-(1-methylethyl)-2-oxazolyl]-2,2'-bipyridine; (R)-6-(4-Isopropyl-2-oxazolin-2-yl)-2,2'-bipyridine; Chiral Bipyridine-Oxazoline Ligand; (R)-iPr-Box-bipyridine; (R)-2,2'-Bipyridin-6-yl-4-isopropyl-4,5-dihydrooxazole
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. For this advanced chiral intermediate, quality is assured through stringent analytical methods including chiral HPLC to confirm enantiomeric purity. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available upon request, supporting your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.