Description

Acetic Acid, 2-[(6-Bromo-3-Pyridinyl)Oxy]-2,2-Difluoro- is a specialized fluorinated pyridine derivative, serving as a high-value building block in advanced organic synthesis. Its molecular structure, featuring a difluoroacetate ester linked to a brominated pyridine ring, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and insecticides, leveraging the bioactivity of the pyridine and fluorine motifs.
• Ligand and Catalyst Development: Serves as a starting material for creating novel ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic electronic materials due to its unique halogenated and fluorinated structure.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	Acetic Acid, 2-[(6-Bromo-3-Pyridinyl)Oxy]-2,2-Difluoro-
CAS No.	2708278-54-8
Molecular Formula	C8H4BrF2NO3
Molecular Weight	280.02 g/mol
Synonyms	2-[(6-Bromo-3-pyridinyl)oxy]-2,2-difluoroacetic acid; Difluoro(6-bromopyridin-3-yloxy)acetic acid; 6-Bromo-3-pyridyl 2,2-difluoro-2-hydroxyacetate; (6-Bromopyridin-3-yl) 2,2-difluoro-2-hydroxyacetate; 2708278-54-8; AcOH, 2-[(6-Br-3-Py)Oxy]-2,2-diF-
EINECS	Contact for details

Quality Control

Every batch of Acetic Acid, 2-[(6-Bromo-3-Pyridinyl)Oxy]-2,2-Difluoro- is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up activities. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by HPLC, NMR, and MS.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its sensitivity, the container should be kept tightly sealed under an inert atmosphere when not in use to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.